Endometriosis Part VI – GnRH Agonists-Definition, Effects,The Good, Risks and side Effects

Endometriosis Part VI – GnRH Agonists-Definition, Effects,The Good, Risks and side Effects

During the last stage of the menstrual cycle normally a layer of endometriosis lining in the inside of the uterus is expelled, known as menstruation blood but instead some of the endometriosis tissues growing somewhere in the body causing endometriosis. Endometriosis also reacts to hormonal signals of the monthly menstrual cycle by building up tissue, breaking it, and eliminating it through the menstrual period. In this article, we will discuss what is what is GnRH(gonadotrophin-releasing hormone) agonists??

I. Definition
GnRH is a hormone released by the hypothalamus which stimulates the pituitary to produce luteinising hormones (LH) and follicle that stimulate hormone (FSH) to drive a menstrual cycle.

II. Effectiveness of GnRH
Just likes progesterone-like agonists, GnRH ( gonadotrophin-releasing hormone) have been used in treating endometriosis for more than 20 years. They come in different forms: three-monthly injection, monthly injection, daily injection and nasal spray because of their chemical make up. GnRH are natural hormone blocking medicines, they help to stop the ovulation and create a temporary menopause state.
Study shows that GnRH are effective in reducing the symptoms and the size of endometrial implants but unfortunately, symptoms tend to return after stopping treatment in 4 months.

Discovering the right The change of life Comfort

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III. The Good
1) It helps to induce a menopause state, thereby reducing symptoms of menstrual cramps.
2.) It also uses to treat heavy menstruation, if other drugs failed.
3) Ovulation usually comes back within a month of stopping the drugs.
4) Reduce symptoms and sizes of endometrial implants because the drug creates the menopause state and stop the ovulation.
5) It can be given as an injection one a month or nostril spray.
6) Endometrial implants may be returned back to it original size within a few months after stop taking the medicine.

III. Risks
1. Loss of bone density
Loss of bone density is normal for women taking the GnRH drug. Since it causes menopause state, it deplete the calcium in the body that is essential for building a healthy bone. It also distorts the ratio of magnesium and calcium.
2) Reducing sexual desire
Sexual libido may be caused by dry vagina, one of many symptoms of GnRH. It may also be caused by low level of estrogen that is essential for driving sexual desire.
3) Increase the risk of developing of ovarian cysts.

IV. Side effects
a) Hot flush, dry vagina caused by temporary of menopause state.
b) Loss of libido caused by low level of estrogen and vagina dryness.
c) Loss of bone density caused by low level of estrogen and progesterone.
d) Nutritional deficiency caused by symptoms of menopause state as our body is no longer absorb magnesium and calcium effectively.

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2 thoughts on “Endometriosis Part VI – GnRH Agonists-Definition, Effects,The Good, Risks and side Effects”

  1. jum

    Mark,
    Hang in there, fellow. Actually, your concerns are quite valid — a woman can become pregnant with mulitples from different men if she is having physical relations with more than one man. Fraternal twins — even if they have the same bio mother and bio father — can also be conceived during separate encounters within a monthly menstrual cycle (fraternal eggs 2 separate eggs that are not necessarily released at the same time/on the same day).

    I would encourage you to pursue this issue. If your suspicions are correct and one of the babies is not biologically yours, it would be best to confront the facts sooner rather than later. I would implore you to include at least one trusted friend or medical professional/therapist in your pursuit before completing any DNA testing.

    Best wishes to you Mark.

  2. wash

    There was a lot of absenteeism where I worked due to menstrual cramps. It was pretty accepted that women would be out for four days each month.

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